Who has lost to Arsenal the most?

Manchester United The team that Arsenal have played most in league competition is Manchester United, who they first met in the 1894–95 Football League season; the 83 defeats from 204 meetings is more than they have lost against any other club.

https://en.wikipedia.org/wiki/Arsenal_F.C._league_record_by_opponent#:~:text=The%20team%20that%20Arsenal%20have,lost%20against%20any%20other%20club.

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